Since composite sandwich structures are susceptible to low-velocity impact damage, a thorough characterization of the loading and damage process during impact is important. In the present paper, the low-velocity impact response of carbon fiber composites lattice structures are investigated by experimental and numerical methods. Impact tests on composite plates are performed using an instrumented drop-weight machine (Instron 9250HV) and a new damage mode is observed. A three-dimensional finite element model is built by ABAQUS/Explicit and user subroutine (VUMAT) to predict the peak loading and simulate the complicated damage problem. It can be found that numerical predictions coincide well with experimental results.