The superhydrophobic and highly oleophobic cotton textile was obtained by applying particle -based in situ fabrication procedure with the low toxic perfluoropolyether (PFPE) and the silica particles. The water contact angle and salad oil contact angle on the treated cotton textile surface can be achieved to 156.8 º and 143.3 º respectively. The microstructure of the treated cotton textile surface was revealed by scanning electron microscopy (SEM). And the chemical composition of the treated cotton textile surface was determined by the X-ray photoelectron spectroscopy (XPS) analysis. Thermogravimetric (TG) analysis showed that the weight loss of the treated cotton is less than that of the untreated sample.