The Cu-based friction material with Ni coated nanometer SiO2 (Ni/n-SiO2) particles was prepared by the powder metallurgy technology. Friction properties of the friction materials were evaluated by a friction tester. The microstructure and worn morphology were characterized by optical microscope (OM) and scanning electric microscope (SEM). The results indicate that the microstructure is uniform. The Ni/n-SiO2 particles can enhance the wear ability of Cu-based friction materials. The wear rate of the friction material with Ni/n-SiO2 is 6.58 times of that without Ni/n-SiO2. The main wear mechanisms are abrasive wear and adhesive wear, and Ni/n-SiO2 particles can reduce the abrasive wear and adhesive wear.