Y2Ti2O7 nanocrystals have been prepared at the calcining temperature of 700-900°C by using tetrabutyl titanate as starting materials and citric acid as chelator. The preparation process was monitored by XRD, FT-IR and TG-DTA analysis. Compared with traditional solid state reaction (SSR), the present used methods can prepare can Y2Ti2O7 nanocrystals at a relatively low temperature (750°C) and with shortened reaction time (dwelling time of 1 h). The morphology and averge size of as-prepared products were analysized by FESEM. Results showed that the as-prepared Y2Ti2O7 with good dispersibility and narrow size-distritution were all sphere-like; the average size was about 40-50 nm, Also, the obtained products had higher BET surface area (32 m2/g). These properties are very helpful for a photocatalytic catalyst to achieve excellent activity.