The results of residual stresses in biocompatible cast Ni-Cr alloys-ceramics joints with an intermediate layer with thickness of about 10μm are discussed. To the experiment were used specimens with dimensions of 45×3×10 mm and 45×4×10 mm made of Cr-Ni alloys-ceramics joint both with and without of application of an intermediate layer. The examinations were carried out by means of metallographical microscope, testing machine and X-ray diffractometer. The measurement of residual macrostresses was carried out by using sin2ψ method. The obtained experimentally values of residual macrostresses are in good agreement with results of numerical simulation performed by means of FEM ANSYS package. The researches have been shown that application of an intermediate ceramics layer influence on increase of strength properties of Ni-Cr alloys-ceramics joints.