A true multi-scale approach is applied for the development of a new meso-macro methodology for modeling of sintering. Sintering distortions of multi-layer and capillary-porous composite powder structures are determined based upon the continuum theory of sintering implemented in a finite-element code. The macroscopic constitutive parameters of the powder material are obtained on the basis of the meso-scale simulations of a realistic grain-pore structure. The model follows both the densification and the damage development during sintering using a new fracture criterion for the prediction of macroscopic strength in sintering. The simulation results are compared with the experimental data on sintering of zirconia, alumina, and Cu powder composites. The modeling results contribute to the development of multi-layer powder metalceramic technologies used for fabrication of components for thermal management of electronic circuitry and wireless communication appliances.