Paper Title:
Nanotechnology-Based Cell Sheet Engineering for Regenerative Medicine
  Abstract

In order to realize true regenerative medicine, we have developed a novel technology for the reconstruction of tissues and organs by utilizing intelligent materials including temperature-responsive polymers. We developed temperature-responsive culture surfaces, on which temperature-responsive polymers are covalently immobilized. Cells are cultured on the surfaces at 37°C, and harvested as transplantable cell sheets by reducing temperature to 20°C. With these cell sheets we regenerate various kinds of tissues such as cornea and heart.

  Info
Periodical
Edited by
P. VINCENZINI and R. BARBUCCI
Pages
74-78
DOI
10.4028/www.scientific.net/AST.53.74
Citation
M. Yamato, T. Okano, "Nanotechnology-Based Cell Sheet Engineering for Regenerative Medicine", Advances in Science and Technology, Vol. 53, pp. 74-78, 2006
Online since
October 2006
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