Paper Title:
Novel Silicon Based Gene Carrier Systems
  Abstract

The preparation and charactersiation of novel gene vehicles based on synthetic organic silicon derivatives are which are formulated as solid lipid nanoparticles (SLN) and liposomes are investigated in the presented study. Physicochemical parameters and morphology were studied by photon correlation spectroscopy, zeta potential measurements (NanoZ Malvern) and Atomic Force Microscopy (Digital Nanoscope IV Bioscope), while the biological activity was determined using a standard in vitro transfection assay and corelated with established gene transfection systems.

  Info
Periodical
Edited by
Pietro VINCENZINI, John A. JANSEN, Kazuhiko ISHIHARA and Thomas J. WEBSTER
Pages
171-176
DOI
10.4028/www.scientific.net/AST.76.171
Citation
A. Sommerwerk, G. Struckmeyer, J. Tillmann, M. Uhr, J. Schäfer, H. Richter, U. Bakowsky, "Novel Silicon Based Gene Carrier Systems", Advances in Science and Technology, Vol. 76, pp. 171-176, 2010
Online since
October 2010
Export
Price
$32.00
Share

In order to see related information, you need to Login.

In order to see related information, you need to Login.

Authors: Martin Reischl, Karin Stana-Kleinschek, Volker Ribitsch
Abstract:The determination of electrokinetic properties such as the zeta-potential of polymer samples with classical methods is laborious and...
1374
Authors: Ding Ding Guo, Rohidas B. Arote, Hu Lin Jiang, Mi Kyong Yoo, Hyun Seuk Moon, Chong Su Cho
Abstract:The objective of this study is to develop a new type of cationic nanoparticles for the intracellular drug delivery to breast cancer....
429
Authors: M. Omastová, M. Mičušík, Pavol Fedorko, M.M. Chehimi, J. Pionteck
Abstract:The surface of multiwall carbon nanotubes (CNT) was modified by non-covalent approach. Various types of surfactants, an anionic surfactant -...
676
Authors: Fang Dan Yu, Yuan Ru Guo, Gui Zhen Fang, Zhi Ming Liu
Abstract:Cationic surfactant, quaternary ammonium salt of lignin, was synthesis from the lignin and trimethylamine though Mannich Reaction. Then...
1045
Authors: Hai Yang Zhang, Ya Li Kuang, Zhe Lin, Chun Hua Liu
Biomaterials
Abstract:Considering the influence on the downstream process of microalgae recovery by cell surface characteristics, in this paper ,...
1938