Paper Title:
Novel Biomaterials and Nano-Biotechnology Approaches in Tumor Diagnosis
  Abstract

Each year 10.9 million people worldwide are diagnosed with cancer and it is the third most common disease in world. Early diagnosis of cancer and cure are major challenges. Recent advances in development of novel biomaterials as well as rapid progress in the area of nano-biotechnology has potentials to change all the current modalities of cancer diagnosis and management. The unique physical and chemical properties of nanomaterials are extremely helpful for detection of biomarkers of the disease, molecular imaging as well as specific targeted therapy sparing the normal organs. Nanoparticle (NP) has large surface area which can be conjugated or coated with different molecular probes for diverse detection system (optical, electrical, magnetic etc.) as well as used as a vehicle to carry different biomolecules and anticancer drugs to tumor cells. Semiconductor quantum dot (QD) with novel optical and electronic properties helped to devise a new class of NP probes for molecular, cellular, and in vivo imaging. A large variety of materials ranging from metal, ceramic, polymer, lipid, protein and nucleic acid are used for developing novel nanoparticles with multiple functions which can detect different aspects of cancer biology and progression. The major issue of concern is biocompatibility and safety of these materials and their fate after in-vivo use. However with collaborative interdisciplinary research it will be possible to develop safer nanomaterials in future

  Info
Periodical
Edited by
Pietro VINCENZINI, John A. JANSEN, Kazuhiko ISHIHARA and Thomas J. WEBSTER
Pages
78-89
DOI
10.4028/www.scientific.net/AST.76.78
Citation
A. K. Dinda, C. K. Prashant, "Novel Biomaterials and Nano-Biotechnology Approaches in Tumor Diagnosis", Advances in Science and Technology, Vol. 76, pp. 78-89, 2010
Online since
October 2010
Export
Price
$32.00
Share

In order to see related information, you need to Login.

In order to see related information, you need to Login.

Authors: Gil Pyo Kim, Seung Bum Yoon, Young Soo Jung, Jae Hoon Ahn, Sung Hyeon Baeck, Alan Kleiman-Schwarsctein, Eric W. Mc Farland
Abstract:Nanoparticles (Au, Pt, Ru) supported on metal oxides (TiO2, Heteropoly Acid) were prepared by PS-PVP block copolymer encapsulation method....
17
Authors: Hyoung Bong Bae, Jung Ho Ryu, Bok Soo Byun, Seong Ho Choi, Sang Ho Kim, Chul Gyun Hwang
Abstract:Pt-Ru@CP-MWNT catalysts were prepared by radiolytic deposition of Pt-Ru nanoparticles on conduction polymer (CP) coated multi walled carbon...
1478
Authors: Yang Yen Yu, Wen Chen Chien, Yu Heng Chou
Abstract:In this study, block copolymers of PS-b-PMSMA with various molecular weight were synthesized by atom transfer radical polymerization (ATRP)....
887
Authors: Adeleh Granmayeh Rad, Hamed Abbasi
Chapter 17: Laser Based Manufacturing
Abstract:In this work we report the preparation of colloidal silver nanoparticles. In order to prepare the silver nanoparticles laser ablation method...
1409
Authors: N.A. Brusentsov, V.A. Polianskiy, A.V. Zhukov, M.V. Gulyaev, Maxim P. Nikitin, P.I. Nikitin, T.N. Brusentsova, V.D. Kuznetsov, O.A. Bocharova, A.Yu. Baryshnikov
Chapter 12: Magnetism in Biology and Medicine
Abstract:As a result of consecutive intravenous injections of combination from 0.05 up to 1.0 ml 1.0-10 % sol Dextran-ferrite (DF), and 0.001-0.02 ml...
757