Paper Title:
Mimicking Bone Architecture in a Metallic Structure
  Abstract

The porous metallic structure has been developed to mimic the natural bone architecture, having interconnected porosity, disposing enough room to cell migration, anchoring, vascularization, nourishing and proliferation of new bone tissue. The titanium is used as porous implants due its excellent mechanical properties and biological interaction. Research evolving porous titanium has been done with purpose to achieve desirable pore size, total porosity percentage and influence of those in the increasing of bone-implant bond strength interface. Were prepared samples of titanium by powder metallurgy adding natural polymer: corn starch, rice starch, potato starch and gelatin; at proportion of 16 wt%. In aqueous solution the hydrogenated metallic powder (TiH2) and the polymer were mixed, homogenized and frozen in molds near net shape. The water was removed in kiln (38°C/12h) and the polymer by thermal treatment with air-oxidation (350 °C/1h) before sintering in high-vacuum (1300 °C/1h). Resulting from the process, the obtained pores by addition of potato and corn starchs, lead to homogenous and well distributed throughout structure. Samples obtained from addition of rice starch and gelatin formed macropores and micropores randomly distributed within the structure. The apparent porosity for all samples was near 40%. The processing technique allowed the open pore formation, in which the macropores mimics the trabecular bone structure and micropores allows the bone-implant anchorage.

  Info
Periodical
Chapter
Chapter 1: Biomimetic Materials
Edited by
Pietro Vincenzini, Luca Schenato, Nadrian C. Seeman and Friedrich C. Simmel
Pages
7-12
DOI
10.4028/www.scientific.net/AST.84.7
Citation
T. S. Goia, K. B. Violin, J. C. Bressiani, A. H. de Almeida Bressiani, "Mimicking Bone Architecture in a Metallic Structure", Advances in Science and Technology, Vol 84, pp. 7-12, Sep. 2012
Online since
September 2012
Price
US$ 28,-
Share
Authors: A. Ravaglioli, A. Krajewski, M. Mazzocchi, Roberta Martinetti, L. Dolcini
1017
Authors: Li Min Dong, Chen Wang, Jie Mo Tian, Jian Pan, Qing Feng Zan
Abstract:Carbonated hydroxyapatite (CHA) bone cement is capable of self-setting and has the component similar to the mineral phase of natural bone....
1545
Authors: Mitsuru Takemoto, Shunsuke Fujibayashi, Masashi Neo, Kazutaka So, Norihiro Akiyama, Tomiharu Matsushita, Tadashi Kokubo, Takashi Nakamura
Abstract:We have developed a porous titanium implant sintered with spacer particles (porosity = 50 %, average pore size ± standard deviation = 303 ±...
987
Authors: Ana Cristina P. Machado, Marize Varella de Oliveira, Robson Pacheco Pereira, Yasmin R. Carvalho, Carlos Alberto Alves Cairo
Abstract:The osseointegration of porous titanium implants was evaluated in the present work. Implants were fabricated from ASTM grade 2 titanium by a...
179
Authors: G. Daculsi, E. Goyenvalle, E. Aguado
Abstract:It was demonstrated that microstructured surfaces improve cell spreading and bone ingrowth. Particularly, the surface roughness modulates the...
795