This paper presents a numerical study of mixed convection heat and mass transfer in horizontal rectangular channels partially filled with porous medium. The main contribution of this research is to characterize how the porous block will create a heterogeneity that will induce a change on the Poiseuille-Rayleigh-Benard (PRB) fluid circulation dynamics. For a broad range of dimensionless parameters, which control the mixed convection, we show that the effect of the insertion of the porous block changes the thermal and solutal boundary layers; we find that the exchanges are intensified near the sidewalls in the porous region compared to upstream and downstream of the porous medium; and inversely in the core region. We describe, also, the onset of the longitudinal rolls at both upstream and downstream of the porous region. And finally, we compared the heat transfer, for different positioning of the porous medium with the purely fluid mixed convection.