Paper Title:
Selective Laser Sintering of Poly(L-Lactide) Porous Scaffolds for Bone Tissue Engineering
  Abstract

The aim of this study was to investigate the feasibility of utilizing selective laser sintering (SLS) to build 3D porous tissue engineering scaffolds from small quantities of poly(L-lactide) (PLLA). PLLA microspheres with suitable particle sizes for the SLS process were produced by the oil-in-water emulsion solvent evaporation technique. A miniature build platform was designed, fabricated and incorporated in an existing Sinterstation® 2000 system to enable small quantities of polymer powder to be used for the production of 3D porous scaffolds. Trial runs were first performed using the DuraForm™ polyamide powder and interfacing problems between the miniature build platform and the existing machine were solved. Then 3D porous scaffolds were successfully built from the PLLA microspheres using the modified SLS machine. This study paved the way for further comprehensive studies on selective laser sintering of tissue engineering scaffolds using expensive biopolymers and their composites.

  Info
Pages
81-89
DOI
10.4028/www.scientific.net/JBBTE.1.81
Citation
S.H. Lee, W. Y. Zhou, M. Wang, W.L. Cheung, W.Y. Ip, "Selective Laser Sintering of Poly(L-Lactide) Porous Scaffolds for Bone Tissue Engineering", Journal of Biomimetics, Biomaterials and Tissue Engineering, Vol. 1, pp. 81-89, 2009
Online since
July 2008
Export
Price
$32.00
Share

In order to see related information, you need to Login.

In order to see related information, you need to Login.

Authors: S.M. Oliveira, C.C. Barrias, C.C. Ribeiro, I.F. Almeida, M.F. Bahia, Mario A. Barbosa
Abstract:The aim of this study was to analyze the effect of starting powder granulometry and sintering conditions on the morphological structure and...
691
Authors: Fan Li, Feng Tian, Chang Jun Liu
Abstract:Poly(3-hydroxybutyrate) (PHB) based microspheres were prepared via double emulsion solvent evaporation using polyethylene glycol (PEG),...
54
Authors: Ju Yang, Dan Qun Huo, Chang Jun Hou, Guo Ping Zhang, Li Min Yang, Yu Chan Zhang, Le Jia Dong, Juan Li
Abstract:A novel protein delivery system with incorporating PLGA microspheres into porous PNIPAAm hydrogel for sustained delivery of proteins was...
1072
Authors: Hirotaka Maeda, Tatsuya Okuyama, Emile Hideki Ishida, Toshihiro Kasuga
Abstract:Novel porous wollastonite microspheres for releasing silicate and calcium ions were prepared by electrospraying using a hydrolyzed alkoxide....
791
Authors: Ming Bo Wang, Jian Xiong, Bin Chu, Rong Wei Tan, Wei Huang, Zhen Ding She
Chapter 2: Advanced Bio and Medical Engineering, Applications of Bioinformatics and Genetic Engineering
Abstract:A kind of PLGA microspheres was prepared with bovine serum albumin (BSA) as the model drug and poly (lactide-co-glycolide) as the matrix. The...
269