A Method to Fabricate Liver Tissue Engineering Scaffold
|Periodical||Journal of Biomimetics, Biomaterials, and Tissue Engineering (Volume 11)|
|Main Theme||Journal of Biomimetics, Biomaterials & Tissue Engineering Vol.11|
|Citation||S. Singare et al., 2011, Journal of Biomimetics, Biomaterials, and Tissue Engineering, 11, 73|
|Online since||September, 2011|
|Authors||S. Singare, Shou Yan Zhong, Zhen Zhong Sun|
|Keywords||Biomaterial, PDMS Mould, Rapid Prototyping (RP), Scaffold, Tissue Engineering|
In this paper, the authors describe a rapid prototyping method to produce vascularized tissue such as liver scaffold for tissue engineering applications. A scaffold with an interconnected channel was designed using a CAD environment. The data were transferred to a Polyjet 3D Printing machine (Eden 250, Object, Israel) to generate the models. Based on the 3D Printing model, a PDMS (polydimethyl-silicone) mould was created which can be used to cast the biodegradable material. The advantages and limitations of Rapid Prototyping (RP) techniques as well as the future direction of RP development in tissue engineering scaffold fabrication were reviewed.