Paper Title:
A Brief Review of the Modelling of the Time Dependent Mechanical Properties of Tissue Engineering Scaffolds
  Abstract

The functionality of tissue scaffolds in vivo plays a critical role in the treatment process. Due to the time dependent nature of the mechanical properties of the constituent phases of the scaffold, a wide range of mechanical property histories may be observed during the treatment process, possibly influencing outcomes. The critical nature of the mechanical properties in load bearing applications indicates a need for the simultaneous modelling of both scaffold degradation and tissue regeneration with time, and the resulting effective properties of the tissue engineering construct. To this end, a review of the literature is conducted to identify the various existing approaches to modelling scaffold degradation, tissue behavior, and the dependency of the two processes on one another.

  Info
Pages
19-33
DOI
10.4028/www.scientific.net/JBBTE.6.19
Citation
N.K. Bawolin, W.J. Zhang, X. B. Chen, "A Brief Review of the Modelling of the Time Dependent Mechanical Properties of Tissue Engineering Scaffolds", Journal of Biomimetics, Biomaterials and Tissue Engineering, Vol. 6, pp. 19-33, 2010
Online since
September 2010
Export
Price
$32.00
Share

In order to see related information, you need to Login.

In order to see related information, you need to Login.

Authors: Zhi Hua Lu, Dong Mei Zhao, Kang Ning Sun
Chapter 11: Biomaterials
Abstract:In this study, a genipin cross linked scaffold containing nano-hydroxyapatite (n-HAp) and carboxymehthyl chitosan (CMCS) was developed by...
2055
Authors: G.R. Mitchell, M. Domingos, Paulo J. Bartolo
I. Plenary and Invited
Abstract:Polymers have a major contribution to make in the field of regenerative medicine in order to develop and deploy biological substitutes that...
11
Authors: Christine Poon, Mei Zhang, Andrew J. Ruys, Angela Hong, Christelle Catuogno, Philip Boughton
Abstract:Tissue engineering of airway tissues poses many complex challenges. As tissue form is determined by function and vice versa, it is necessary...
31
Authors: Xue Zhang, Xiao Wu Li, Ji Guang Li, Xu Dong Sun
Chapter 3: Mechanical and Physical Properties
Abstract:Magnesium has been recently recognized as a biodegradable metal for bone substitute applications. In the present work, a novel magnesium...
276
Authors: Bing Hui Li, Yong Yu, Dan Xu
Chapter 1: Bio-, Chemical, Food Materials, Material Engineering and Technology
Abstract:The development of tissue engineering techniques for cartilage repair and regeneration provided a new way, according to their own...
68