This review paper presents a fail-safe approach in designing biomaterials against wear for application in an artificial total hip replacement in view of the recent advances in orthopedic bioengineering materials. It has been established that substantially different alloys should be used for minimizing wear in bearing surfaces. Frictional forces at these rubbing counter-faces must be minimized to prevent loosening of the femoral stem and acetabular socket assembly from their positions secured by the fixation agent. A comparative analysis of various wear-resistant biomaterials resulted in the lowest production of wear particles in a total hip where a ceramic socket articulates against the ceramic ball: it produces only 0.004 cubic millimeters of ceramic wear particles. Surface modification, through the application of coatings, offers the potential to reduce the wear rate without compromising the bulk mechanical behavior of the implant material. These hard coatings were found to include diamond-like carbon, amorphous diamond, and titanium nitride.