We report the sonochemical synthesis of mercury telluride (HgTe) nanoparticles and the photocurrents of these nanoparticles and their organic hybrid system. The HgTe nanoparticles were about 5 nm in size and their lattice structure was cubic. Poly(N-vinylcarbazole)(PVK) was added to the HgTe nanoparticles for the formation of an inorganic(HgTe)-organic(PVK) hybrid system. The room-temperature photocurrents of the HgTe nanoparticles and the HgTe-PVK hybrid system were compared in this study. The photocurrent was significantly enhanced for the HgTe-PVK hybrid system.