TiB2 -Cu cermet with the relative density of 92% was produced from titanium, boron and copper powders by combustion synthesis and subsequently pseudo hot isostatic pressing. To improve its mechanical and thermal physical properties, the two-time hot pressing sintering test was carried out at 1050°, 1090° and 1150°C respectively. The deformation behavior and variation of micro- structure and mechanical properties were investigated in detail. The results showed that the relative density and the flexural strength increase remarkably after two-time hot pressing. The relative density reaches 605.5MPa and the flexural strength reaches 96% when the two-time pressing temperature is at 1090°C, and the values increase 12% and 6% compared to that before two-time pressing.