Brushite cement is more soluble than apatite cement in physiological conditions and therefore may be more resorbable in vivo. Brushite cement has been formed previously by mixing β-tricalcium phosphate, water and an acidic source of phosphate ions. However, brushite cement may be formed by the mixture of H3PO4 solution and poorly crystalline precipitated hydroxyapatite (HA). Several additives have been used to alter the physicochemical properties of brushite cement. In this study sulphate ions where added to the cement system by addition of ammonium sulphate to HA during HA preperation. Sulphate ions were found to alter the structure, composition and mechanical performance of cement.