Silicon containing self setting bone cement has been prepared by adding silicon containing hydroxyapatite whisker to obtain a biomaterial having an improved resorption properties. Silicon containing calcium phosphate bone cement was composed of a-TCP: TeCP: DCPD: Si-HA whisker with a NH4H2PO4 as a setting liquid. From the XRD analysis, it was confirmed that calcium deficient hydroxyapatite phase appeared when it immersed in PBS solution. The dissolution rate of silicon containing calcium phosphate cement was measured in PBS solution and showed high dissolution rate. Based on in-vivo test, silicon containing self setting bone cement can be considered a useful material for bone bonding materials.