Paper Title:
Preparation of Porous Biphasic Tricalcium Phosphate and Its In Vivo Behavior
  Abstract

Biphasic ceramic consisting of tricalcium phosphate with α- and β -phases (αβ-TCP) is a candidate as biodegradable bone substitutes since its biodegradability may be controlled by the ratio of the phases. In the present study, preparation of porous αβ-TCP body with continuous pores of 10-50 µm in diameter was attempted using additives of Mg, and its in vivo behavior was examined. Powder of β-TCP was mixed with Mg and potato starch to form slurry, followed by loading in polyurethane foam. The sample was fired at 1400°C for 12 hours for sintering process. α-TCP content of the sample decreased with increasing the Mg content, while β-TCP increased. Ceramic body consisting of β-TCP phase was obtained when 1.0 mass% of Mg was added. Porosity of the body decreased with increasing the content of Mg. The αβ-TCP body with 80% porosity was obtained when the content of Mg was 0.1 mass%. The in vivo experiments showed that the rate of degradation of the obtained αβ-TCP was almost same as α-TCP, and much higher than β-TCP.

  Info
Periodical
Key Engineering Materials (Volumes 284-286)
Main Theme
Edited by
Panjian Li, Kai Zhang and Clifford W. Colwell, Jr.
Pages
281-284
DOI
10.4028/www.scientific.net/KEM.284-286.281
Citation
M. Kamitakahara, C. Ohtsuki, M. Oishi, S. Ogata, T. Miyazaki, M. Tanihara, "Preparation of Porous Biphasic Tricalcium Phosphate and Its In Vivo Behavior ", Key Engineering Materials, Vols. 284-286, pp. 281-284, 2005
Online since
April 2005
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Price
$32.00
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