Paper Title:
Fabrication of Porous Calcium Phosphate Bioceramics as Synthetic Cortical Bone Graft
  Abstract

The aim of this study was to fabricate porous Hydroxyapatite/Tricalcium phosphate (HA/TCP) bioceramics with an adequate degree of interconnected porosity combined with optimal mechanical properties. Porous HA/TCP bioceramics with interconnected porosity and the controlled pore sizes necessary to simulate natural bone tissue morphology were fabricated by a novel technique of vacuum impregnation of reticulated polymeric foams with ceramic slip. By varying the characteristics of the slips and using foams of different pores per inch (ppi), samples of porous HA/TCP, blocks and granules, with a wide range of pore sizes were successfully manufactured. Functionally gradient materials (FGM) with porosity gradients were also made and no weakness was found at the interface. The pore size of the HA/TCP bioceramics was in the range of 197 – 254 µm (for 20 ppi foam), 143 – 182 µm (for 30 ppi foam) and 105 – 127 µm (for 45 ppi foam). The compressive strengths and the apparent densities of the HA/TCP samples were in the range of 30 –170 MPa and 2.34 – 2.76 g/cm3 respectively. These results indicate that it is possible to manufacture open pore HA/TCP bioceramics with compressive strengths comparable to human bone which could be of clinical interest.

  Info
Periodical
Key Engineering Materials (Volumes 284-286)
Main Theme
Edited by
Panjian Li, Kai Zhang and Clifford W. Colwell, Jr.
Pages
305-308
DOI
10.4028/www.scientific.net/KEM.284-286.305
Citation
Y.H. Hsu, I.G. Turner, A.W. Miles, "Fabrication of Porous Calcium Phosphate Bioceramics as Synthetic Cortical Bone Graft", Key Engineering Materials, Vols. 284-286, pp. 305-308, 2005
Online since
April 2005
Export
Price
$32.00
Share

In order to see related information, you need to Login.

In order to see related information, you need to Login.

Authors: X. Miao, Ying Hu, J. Liu, B. Tio, P. Cheang, Khiam Aik Khor
595
Authors: J.P. Gittings, I.G. Turner, A.W. Miles
Abstract:Calcium phosphate (CaP) ceramics possessing an interconnecting porosity network in the appropriate size range for vascularisation offer the...
349
Authors: G. Daculsi, P. Corre, Oliver Malard, Racquel Z. LeGeros, Eric Goyenvalle
Abstract:Calcium phosphate bioceramics and bovine bone xenograft with or without sintering are more or less used in orthopaedics or in maxillofacial...
1379
Authors: Y.H. Hsu, I.G. Turner, A.W. Miles
Abstract:Ceramic slips with powder loadings in the range of 80-140 wt% were used to investigate the effect of slip loading on the physical and...
19