Paper Title:
Biodegradation of Porous Alpha-Tricalcium Phosphate Coated with Silk Sericin
  Abstract

Porous a-tricalcium phosphate (a-TCP) ceramics are attractive as a novel bioresorbable material for bone repair, since they can be easily fabricated through conventional sintering of b-TCP at high temperature. However, the solubility of a-TCP is too high to keep its body until the bone defect is repaired completely. Coating of the a-TCP porous body with organic polymer is a way to reduce the degradation rate. In the present study, biodegradation of a-TCP porous body coated with silk sericin was evaluated in vivo. Bone repair at the defect made in rabbit tibia was nearly completed after 4 weeks. Higher density of cortical bone was estimated for a-TCP coated with sericin than for mere a-TCP. The a-TCP porous body coated with sericin is expected as a material that show less degradation than mere a-TCP, and may result in suitable bone repair.

  Info
Periodical
Key Engineering Materials (Volumes 284-286)
Main Theme
Edited by
Panjian Li, Kai Zhang and Clifford W. Colwell, Jr.
Pages
329-332
DOI
10.4028/www.scientific.net/KEM.284-286.329
Citation
A. Takeuchi, C. Ohtsuki, M. Kamitakahara, S. Ogata, M. Tanihara, T. Miyazaki, M. Yamazaki, Y. Furutani, H. Kinoshita, "Biodegradation of Porous Alpha-Tricalcium Phosphate Coated with Silk Sericin", Key Engineering Materials, Vols. 284-286, pp. 329-332, 2005
Online since
April 2005
Export
Price
$32.00
Share

In order to see related information, you need to Login.

In order to see related information, you need to Login.

Authors: P.C. Xia, Jin Jiang Yu, Xiao Feng Sun, Heng Rong Guan, Zhuang Qi Hu
Abstract:Effect of different aging temperatures on microstructure and stress rupture properties of DZ951 alloy were investigated in this paper. The...
1241
Authors: David Geist, Christian Rentenberger, Hans Peter Karnthaler
Abstract:The L12-structured intermetallic compound Zr3Al can be rendered amorphous easily by several techniques. In the present study the structural...
553
  | Authors: Thomas Link, Alexander Epishin, Nils Nawrath, Catrina Michel, Mohamed Nazmy
Abstract:The single crystal superalloys CMSX-4 and TMS75 were tested for very long times at high temperatures in laboratory creep tests and in...
25
Authors: Keh Moh Lin, Yang Hsien Lee, Wen Yeong Huang, Po Chun Hsu, Chin Yang Huang, Zhu Fu Hsieh
Chapter 02: Testing and Analysis Techniques of Material
Abstract:To find out the important factors which decisively affect the soldering quality of photovoltaic modules, solar cells were soldered under...
188
Authors: Jia Ming Rui
Chapter 1: Materials Engineering and Chemistry. Research and Technologies of Manufacturing and Processing
Abstract:In this study, a novel type of corona-resistance polyimide/spherical SiO2 hybrid films based on 3,3,4,4-biphenyltetracarboxylic...
172