Drug Loaded Porous Hydroxyapatite and Its In Vitro Release |
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| Journal | Key Engineering Materials (Volumes 284 - 286) |
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| Volume | Bioceramics 17 |
| Edited by | Panjian Li, Kai Zhang and Clifford W. Colwell, Jr. |
| Pages | 423-426 |
| DOI | 10.4028/www.scientific.net/KEM.284-286.423 |
| Citation | Young Hee Kim et al., 2005, Key Engineering Materials, 284-286, 423 |
| Online since | April, 2005 |
| Authors | Young Hee Kim, B.G. Song, Soo Ryong Kim, Kwang Jin Kim |
| Keywords | Controlled-Release, Hydroxyapatite (HA), Ibuprofen, Mesoporous Silica, Simulated Body Fluid (SBF) |
| Abstract | Porous hydroxyapatite coated with mesoporous silica has been utilized as the matrix for controlled drug delivery. TEM observation confirms the pore size of mesoporous silica scatters about 50 Å. Porous hydroxyapatite was coated with mesoporous silica via sol-gel process. Ibuprofen and was loaded into the pores of mesoporous silica, and controlled release profiles were studied by soaking the samples in a simulated body fluid using a UV-VIS spectrophotometer. |
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