Paper Title:
The Influence of Geometrically Configured Sol-Gel Derived Hydroxyapatite Substrates on Osteoblast Response
  Abstract

Good quality crystalline sol-derived Hydroxyapatite (HA) thin films of thickness ~350 nm on titanium substrates with underlying micro-channels were prepared by microwave annealing at a temperature of 400 °C for 30 min. A comprehensive in-vitro study was conducted to assess the osteoblast adhesive response to the well-defined micro-scale topographical features on HA coated and uncoated surfaces. The study confirmed the osteoblast’s response to the HA coated micro-channels with an elongated morphology. The effects to morphology suggest that osteoblast adhesion can be improved through optimal micro-channel design and may provide baseline design cues for improving the longterm performance of prosthetic orthopedic and dental implants.

  Info
Periodical
Key Engineering Materials (Volumes 284-286)
Main Theme
Edited by
Panjian Li, Kai Zhang and Clifford W. Colwell, Jr.
Pages
569-572
DOI
10.4028/www.scientific.net/KEM.284-286.569
Citation
D. Adams, R. D. Smith, G. F. Malgas, S.P. Massia, T.L. Alford, J.W. Mayer, "The Influence of Geometrically Configured Sol-Gel Derived Hydroxyapatite Substrates on Osteoblast Response ", Key Engineering Materials, Vols. 284-286, pp. 569-572, 2005
Online since
April 2005
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Price
$32.00
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