Paper Title:
In Situ Monitoring of Chondrocyte Response to Bioactive Scaffolds Using Raman Spectroscopy
  Abstract

Septal cartilage is widely used for the repair of soft tissue defects in the head, neck and nose. Tissue Engineering techniques are being investigated to create cartilage in vitro by seeding appropriate cells on resorbable scaffolds. In this study, human chondrocytes were cultured on macroporous bioactive glass foam scaffolds. The aim was to investigate how Raman spectroscopy could be used as a non-invasive technique to monitor the response of chondrocytes to a 3D scaffold in real time. The spectra were compared to scanning electron microscope (SEM) micrographs and immunohistochemistry results.

  Info
Periodical
Key Engineering Materials (Volumes 284-286)
Main Theme
Edited by
Panjian Li, Kai Zhang and Clifford W. Colwell, Jr.
Pages
623-626
DOI
10.4028/www.scientific.net/KEM.284-286.623
Citation
J. R. Jones, A. Vats, I. Notingher, J. E. Gough, N. S. Tolley, J. M. Polak, L. L. Hench, "In Situ Monitoring of Chondrocyte Response to Bioactive Scaffolds Using Raman Spectroscopy ", Key Engineering Materials, Vols. 284-286, pp. 623-626, 2005
Online since
April 2005
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Price
$32.00
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