Paper Title:
Blood Compatibility of Organic-Inorganic Biomedical Materials
  Abstract

Organic-inorganic hybrids involving Ti-O bonds were coated on stainless-steel (SUS316L)substrates. Tetraisopropoxide and titanium methacrylate triisopropoxide were employed as the major starting chemicals to provide TiO2-polydimethylsiloxane (PDMS) layers or organotitanium molecular thin layers, respectively. Fourier transform infrared spectra indicated that each layer contained Ti-O bonds in their structure. The obtained hybrid layers had little effects on the blood-clotting times such as active partial thromboplastin time and prothrombin time. In addition, the number of adhered platelet on the TiO2-PDMS layers depended on the composition, while the organotitanium molecular thin layers suppressed fibrinogen adsorption compared with coating-free SUS 316L substrate.

  Info
Periodical
Key Engineering Materials (Volumes 284-286)
Main Theme
Edited by
Panjian Li, Kai Zhang and Clifford W. Colwell, Jr.
Pages
713-716
DOI
10.4028/www.scientific.net/KEM.284-286.713
Citation
A. Osaka, T. Yoshioka, T. Yabuta, K. Tsuru, S. Hayakawa, "Blood Compatibility of Organic-Inorganic Biomedical Materials ", Key Engineering Materials, Vols. 284-286, pp. 713-716, 2005
Online since
April 2005
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Price
$32.00
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