Paper Title:

Apatite Formation on Organic-Inorganic Hybrid Containing Sulfonic Group

Periodical Key Engineering Materials (Volumes 284 - 286)
Main Theme Bioceramics 17
Edited by Panjian Li, Kai Zhang and Clifford W. Colwell, Jr.
Pages 725-728
DOI 10.4028/www.scientific.net/KEM.284-286.725
Citation Toshiki Miyazaki et al., 2005, Key Engineering Materials, 284-286, 725
Online since April, 2005
Authors Toshiki Miyazaki, Moriyoshi Imamura, Eiichi Ishida, Masahiro Ashizuka, Chikara Ohtsuki, Masao Tanihara
Keywords Apatite, Bioactivity, Organic-Inorganic Hybrid, Simulated Body Fluid (SBF), Sulfonic Group
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Abstract

Apatite formation in living body is essential condition for artificial materials to exhibit bone-bonding ability, i.e. bioactivity. It has been recently revealed that sulfonic group triggers apatite nucleation in body environment. Organic-inorganic hybrids consisting of organic polymer and the sulfonic group are therefore expected to be useful for novel bone-repairing materials exhibiting flexibility as well as bioactivity. In the present study, organic-inorganic hybrids were prepared from vinylsulfonic acid sodium salt and hydroxyethylmethacrylate (HEMA), a kind of acrylic polymer. Bioactivity of the hybrids was assessed in vitro by examining their acceptance of apatite formation in simulated body fluid (SBF, Kokubo solution). The obtained hybrids showed the apatite deposition after soaking in SBF within 7 d.