Paper Title:
In Vitro Cytotoxicity of Alginate-Encapsulating Ferrite Particles Using WST-1
  Abstract

The purpose of this study was to evaluate the cytotoxicity of alginate-encapsulting ferrite particles in vitro. Various ferrite particles such as Ba-ferrite, Sr-ferrite, Co-ferrite, Co/Ni-ferrite were prepared by sol-gel process. Ferrite particles were encapsulated via calcium alginate process with different alginate contents ranged from 10 to 100 wt%. Mouse-fibroblastic NCTC L-929 cells were cultured in RPMI-1640 medium with 10% fetal bovine serum. The alginate-encapsulating ferrites were extracted in 5 ml of distilled water under pH 6.5 at 121°C for 1 h in accordance with ISO 10993-12. In vitro cytotoxicity was evaluated by WST-1. The results of this study indicated that the alginate-encapsulting ferrite particles affected cell viability by increasing alginate contents. Especially, alginate-encapsulating process were enhanced cell viability of ferrites such as Sr-ferrite, Co/Ni-ferrite, and Ba-Ferrite when alginate content was 10 wt%.

  Info
Periodical
Key Engineering Materials (Volumes 284-286)
Main Theme
Edited by
Panjian Li, Kai Zhang and Clifford W. Colwell, Jr.
Pages
815-818
DOI
10.4028/www.scientific.net/KEM.284-286.815
Citation
S. B. Lee, S. H. Lee, D.H. Kim, D. Y. Lee, Y. K. Lee, K. N. Kim, K. M. Kim, "In Vitro Cytotoxicity of Alginate-Encapsulating Ferrite Particles Using WST-1", Key Engineering Materials, Vols. 284-286, pp. 815-818, 2005
Online since
April 2005
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Price
$35.00
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