Paper Title:
In Vitro Biodegradability of Chitosan-Organosiloxane Hybrid Membrane
  Abstract

Chitosan-silicate hybrid membranes were prepared using g-glycidoxy-propyltrimethoxysilane (GPSM) through a sol-gel process. The amino groups of chitosan chains were reacted with the epoxy groups of GPSM and GPSM have a function as the agent to cross-link the chitosan chains. The cross-linking degree of the hybrid membranes was determined by ninhydrin assay. Fourier-transform infrared (FT-IR) spectroscopy and 29Si cross-polarization (CP) magic-angle spinning (MAS)-NMR spectroscopy were used to assess the structure of the hybrid membranes. The biodegradability of the hybrid membranes in phosphate-buffered saline solution or lysozyme solution was investigated as a function of the GPSM concentration.

  Info
Periodical
Key Engineering Materials (Volumes 284-286)
Main Theme
Edited by
Panjian Li, Kai Zhang and Clifford W. Colwell, Jr.
Pages
823-826
DOI
10.4028/www.scientific.net/KEM.284-286.823
Citation
K. Tsuru, Y. Shirosaki, S. Hayakawa, A. Osaka, M.A. Lopes, J. D. Santos, M. H. F.V. Fernandes, "In Vitro Biodegradability of Chitosan-Organosiloxane Hybrid Membrane", Key Engineering Materials, Vols. 284-286, pp. 823-826, 2005
Online since
April 2005
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$32.00
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