Paper Title:
Assessment of the Potential of Bonelike® Graft for Bone Regeneration by Using an Animal Model
  Abstract

BonelikeÒ graft that mimics the inorganic composition of bone tissue has been developed and characterized over the last decade. To evaluate the osteoconductivity of BonelikeÒ two granule size ranges, one ranging from 150-250µm and the other from 250-500µm were implanted in the femurs of New Zealand White rabbits, aiming at being clinically used in different medical applications, such as dentistry and orthopaedics. In order to facilitate the medical application of the BonelikeÒ graft the use of a commercially available polymeric vehicle was also analyzed. Radiological examination, histological studies and scanning electron microscopy (SEM) analyses revealed that the surface of Bonelike® granules was almost completely surrounded by new bone formation after 12 weeks of implantation, which proves its highly osteoconductive behaviour.

  Info
Periodical
Key Engineering Materials (Volumes 284-286)
Main Theme
Edited by
Panjian Li, Kai Zhang and Clifford W. Colwell, Jr.
Pages
877-880
DOI
10.4028/www.scientific.net/KEM.284-286.877
Citation
J.V. Lobato, N. Sooraj Hussain, C.M. Botelho, J.M. Rodrigues, A.L. Luís, A. C. Maurício, M.A. Lopes, J. D. Santos, "Assessment of the Potential of Bonelike® Graft for Bone Regeneration by Using an Animal Model ", Key Engineering Materials, Vols. 284-286, pp. 877-880, 2005
Online since
April 2005
Export
Price
$32.00
Share

In order to see related information, you need to Login.

In order to see related information, you need to Login.

Authors: H. Teramoto, A. Kawai, S. Sugihara, A. Yoshida, Hisahiro Inoue
269
Authors: M. Gutierres, N. Sooraj Hussain, A. Afonso, L. Almeida, T. Cabral, M.A. Lopes, José D. Santos
Abstract:This paper reports the ability of Bonelike® to regenerate bone defected areas when implanted in the tibia of 3 patients (average age of 59...
1041
Authors: Christophe Drouet, Ronan Barré, Gérard Brunel, Gérard Dechambre, Edmond Benqué, Christèle Combes, Christian Rey
Abstract:Apatite/β−TCP particles exhibiting non-conventional urchin-like morphology were prepared by hydrothermal synthesis. Their implantation in...
1237
Authors: C.S. Lim, S.G. Kim, Sung Chul Lim
Abstract:We evaluated the bone healing effect of grafting with synthetic β-tricalcium phosphate (β-TCP; Cerasorb®), bovine-derived hydroxyapatite...
1261
Authors: G.V.O. Fernandes, Monica Calasans-Maia, F.F. Mitri, Vagner Gonçalves Bernardo, Antonella M. Rossi, G.D.S. Almeida, José Mauro Granjeiro
Abstract:Biomaterials for treatment of bone defects have been studied for a long time. Alloplastic materials, mainly hydroxyapatite (HA), are under...
15