Paper Title:
Preparation of Electrospun PLA Nanofiber Scaffold and the Evaluation In Vitro
  Abstract

A electrospinning process to prepare soft tissue engineering scaffold was introduced in this study. This kind of scaffold was composed with ultrathin fiber and characterized with high porosity, well-interconnected pores and high surface-to-volume ratio. Biodegradable polylaticacid (PLA) was used to spin the scaffold and the scaffold was evaluated in vitro by analysis the microscopic structure, porosity, mechanical property, especially cytocompatibility. The results indicated that the electrospun PLA scaffold showed good cytocompatibility and the tensile property of electrospun scaffold was similar to human’s soft tissue. It could be expected that the electrospun scaffold would be potential in soft tissue engineering or soft tissue repair.

  Info
Periodical
Key Engineering Materials (Volumes 288-289)
Edited by
Xingdong Zhang, Junzo Tanaka, Yaoting Yu and Yasuhiko Tabata
Pages
139-142
DOI
10.4028/www.scientific.net/KEM.288-289.139
Citation
X. T. Wen, H. S. Fan, Y. F. Tan, H.D. Cao, H. Li, B. Cai, X. D. Zhang, "Preparation of Electrospun PLA Nanofiber Scaffold and the Evaluation In Vitro", Key Engineering Materials, Vols. 288-289, pp. 139-142, 2005
Online since
June 2005
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Price
$32.00
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