Paper Title:
A Dissolvable Intralumental Stent for Sutureless Vascular Anastomasis
  Abstract

A soluble intralumenal stent for vascular anastomosis was prepared from glucose, Dextran-40 and heparin. The solubility of the stent was tested in vitro and in vivo. Animal tests were carried out with femoral arteries of rabbits. In comparison with the literature reported surgar and poly(ethylene glycol, PEG) stents, shorter dissolving time and higher patency (or survival) rate were obtained. Cell culture experiments suggested that the heparin containing glucose and Dextran-40 stent (H-sugar) had no irritation and toxicity to the endothelia cells. No thrombosis was observed from the in vivo tests in 2 months after the anastomosis. Such a heparin containing sugar stent is a promising candidate for fast sutureless anastomosis of vessels in non-trauma surgery.

  Info
Periodical
Key Engineering Materials (Volumes 288-289)
Edited by
Xingdong Zhang, Junzo Tanaka, Yaoting Yu and Yasuhiko Tabata
Pages
575-578
DOI
10.4028/www.scientific.net/KEM.288-289.575
Citation
X. H. Wang, X.D. Liang, Z. Xiong, Y. N. Yan, R. Zhang, F. Lin, R. D. Wu, Q. P. Lu, Y. W. Fang, "A Dissolvable Intralumental Stent for Sutureless Vascular Anastomasis", Key Engineering Materials, Vols. 288-289, pp. 575-578, 2005
Online since
June 2005
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Price
$32.00
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