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Biodegradable Polymer Scaffold for Tissue Engineering

Journal Key Engineering Materials (Volumes 288 - 289)
Volume Advanced Biomaterials VI
Edited by Xingdong Zhang, Junzo Tanaka, Yaoting Yu and Yasuhiko Tabata
Pages 59-62
DOI 10.4028/www.scientific.net/KEM.288-289.59
Online since June, 2005
Authors Tetsuya Tateishi, Guo Ping Chen
Keywords Articular Cartilage, Biodegradable Polymer, Hybrid Mesh, Hybrid Sponge, Tissue Engineering
Abstract A new method for the preparation of biodegradable porous scaffolds has been developed by using preprepared ice particulates as porogen material. A novel kind of hybrid biodegradable porous scaffold has been developed by forming collagen microsponges in the pores or interstices of a synthetic polymer sponge or mesh. A hybrid sponge of synthetic polymer, collagen and hydroxyapatite has been developed for hard tissue engineering. Bovine articular cartilage-like tissue has been engineered by culturing chondrocytes in the PLGA-collagen scaffolds.
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