Paper Title:
Poly-N-Acetyl Glucosamine as a Scaffold for Cartilage Tissue Engineering in Nude Mice
  Abstract

Athymic nude mice were used as an animal model to evaluate the chondrogenic effects of bovine fetal chondrocytes seeded onto a new poly-N-acetyl glucosamine sponge. Results show excellent hyaline-like cartilage formation with high glycosaminoglycan concentration after 6 weeks. At 4 weeks there is less cartilage formation and more fibrous tissue infiltrate. Although further studies are needed, these initial data support the use of poly-N-acetyl glucosamine sponge as a scaffold for cartilage tissue engineering.

  Info
Periodical
Key Engineering Materials (Volumes 288-289)
Edited by
Xingdong Zhang, Junzo Tanaka, Yaoting Yu and Yasuhiko Tabata
Pages
71-74
DOI
10.4028/www.scientific.net/KEM.288-289.71
Citation
C. M. Hill, Y. H. An, Q. K. Kang, M. V. Demcheva, S.W. Whitson, J. Vournakis, "Poly-N-Acetyl Glucosamine as a Scaffold for Cartilage Tissue Engineering in Nude Mice", Key Engineering Materials, Vols. 288-289, pp. 71-74, 2005
Online since
June 2005
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Price
$32.00
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