JIS-SPV50Q high strength steel is often employed in construction of liquid petroleum gas (LPG) spherical tanks due to its high strength and good ductility. In general, post weld heat treatment is not performed after welding of SPV50Q high strength steel and welding residual stress will be retained in weldment. Service experience and inspection indicate that higher H2S concentration and welding residual stress result in the environmental failure, such as blistering or hydrogen induced cracking (HIC), sulfide stress corrosion cracking (SSCC) and stress oriented hydrogen induced cracking (SOHIC). In the present paper, the cracking behavior of SPV50Q high strength steel weldment by manual electric arc welding has been investigated in various saturate solutions with different concentrations of H2S. The results of slow strain rate testing, performed at a strain of 1×10-6s-1, reveal the presence of SSCC and HIC in the base metal adjacent to HAZ. The ffects of the different temperatures of post weld heat treatment on cracking are discussed. The suitable post weld heat treatment could increase the resistance of SPV50Q weldment on SSCC or HIC and does not decrease the mechanical properties of SPV50Q weldment.