Paper Title:
Effect of OH Content on the Bioactivity of Sol-Gel Derived Glass Foam Scaffolds
  Abstract

Bioactive glass scaffolds have been developed with interconnected macropore networks, with pore diameters in excess of 500µm and apertures in excess of 100µm, by foaming sol-gel derived bioactive glasses. Bioactive glasses bond to bone by forming a hydroxycarbonate apatite (HCA) layer on their surface on contact with body fluid, which is similar to the composition of the apatite in bone. The aim of this work was to investigate the how changing the atomic structure of the glass affects HCA layer formation. Scaffolds were synthesised at 3 sintering temperatures and were characterised using 29Si and proton MAS-NMR, from which the silica network connectivity and Si-OH groups were quantified. The rate of HCA layer formation decreased as the number of Si-OH groups decreased, confirming the role of Si-OH groups in HCA layer formation.

  Info
Periodical
Key Engineering Materials (Volumes 309-311)
Main Theme
Edited by
Takashi Nakamura, Kimihiro Yamashita and Masashi Neo
Pages
1031-1034
DOI
10.4028/www.scientific.net/KEM.309-311.1031
Citation
J. R. Jones, T.F. Kemp, M.E. Smith, "Effect of OH Content on the Bioactivity of Sol-Gel Derived Glass Foam Scaffolds ", Key Engineering Materials, Vols. 309-311, pp. 1031-1034, 2006
Online since
May 2006
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$32.00
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