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A New Way to Prepare Porous Polylactide /Hydroxyapatite Scaffold at Room Temperature

Journal Key Engineering Materials (Volumes 309 - 311)
Volume Bioceramics 18
Edited by Takashi Nakamura, Kimihiro Yamashita and Masashi Neo
Pages 1083-1086
DOI 10.4028/www.scientific.net/KEM.309-311.1083
Citation Yi Wang et al., 2006, Key Engineering Materials, 309-311, 1083
Online since May, 2006
Authors Yi Wang, Hong Song Fan, Yu Mei Xiao, Zhong Wei Gu, Xing Dong Zhang
Keywords Composite, Hydroxyapatite (HA), Poly(lactic acid) (PLA), Porous Scaffold
Abstract

A new way to prepare polymer/hydroxyapatite(HA) composite scaffolds with 3-D interconnected macro and micro pores at room temperature was established, basically based on solvent-casting and particle-leaching together with foaming technique. With this method, Polylactide (PLA) / HA composites of porous architecture with macro pores (50~300)m, average 200)m) and micro pores (~10)m) on the skeleton were obtained. The bending strength and the compressive strength of the composite scaffold were reached to 11.5 MPa and 7MPa respectively with the porosity of approximate to 90%. The study supplied a new short time, low energyexpending method to prepare polymer/ceramic composite with high porosity and interconnected porous structure at room temperature.

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