Paper Title:
Evaluation of Pore Architecture in Hydroxyapatite/Collagen Scaffold Using Micro Computed Tomography
  Abstract

Hydroxyapatite/collagen (HAp/Col) composite scaffold with unidirectionally elongated pores (scaffold-U) was fabricated by the unidirectional solidification with ice growth and subsequent freeze-dry process. The pore architecture in the composite was evaluated by using scanning electron microscopy (SEM) and micro computed tomography (micro-CT) with a high resolution. The SEM observation showed that the scaffold-U had unidirectional pores elongated along the vertical direction (i.e. ice growth direction), however the horizontal cross-section showed quite different pore morphology: spindle-shaped pores with random direction. The 3-D micro-CT image of the scaffold-U simultaneously showed the microstructure of the unidirectionally elongated pore and the cross-sectional pore, indicating that the interconnected micropores were successfully fabricated along the ice growth direction. The micro-CT is a powerful tool for the visualization of 3-D pore structure.

  Info
Periodical
Key Engineering Materials (Volumes 309-311)
Main Theme
Edited by
Takashi Nakamura, Kimihiro Yamashita and Masashi Neo
Pages
1091-1094
DOI
10.4028/www.scientific.net/KEM.309-311.1091
Citation
S. Yunoki, T. Ikoma, A. Monkawa, K. Ohta, M. Kikuchi, M. Tanaka, "Evaluation of Pore Architecture in Hydroxyapatite/Collagen Scaffold Using Micro Computed Tomography ", Key Engineering Materials, Vols. 309-311, pp. 1091-1094, 2006
Online since
May 2006
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