Paper Title:
Biomimetic Apatite Formation on Different Polymeric Microspheres Modified with Calcium Silicate Solutions
  Abstract

Bioactive polymeric microspheres can be produced by pre-coating them with a calcium silicate solution and the subsequent soaking in a simulated body fluid (SBF). Such combination should allow for the development of bioactive microspheres for several applications in the medical field including tissue engineering. In this work, three types of polymeric microspheres with different sizes were used: (i) ethylene-vinyl alcohol co-polymer (20-30 'm), (ii) polyamide 12 (10-30 'm) and (iii) polyamide 12 (300 'm). These microspheres were soaked in a calcium silicate solution at 36.5°C for different periods of time under several conditions. Afterwards, they were dried in air at 100°C for 24 hrs. Then, the samples were soaked in SBF for 1, 3 and 7 days. Fourier transformed infrared spectroscopy, thin-film X-ray diffraction, and scanning electron microscopy showed that after the calcium silicate treatment and the subsequent soaking in SBF, the microspheres successfully formed a bonelike apatite layer on their surfaces in SBF within 7 days due to the formation of silanol (Si-OH) groups that are quite effective for apatite formation.

  Info
Periodical
Key Engineering Materials (Volumes 309-311)
Main Theme
Edited by
Takashi Nakamura, Kimihiro Yamashita and Masashi Neo
Pages
279-282
DOI
10.4028/www.scientific.net/KEM.309-311.279
Citation
I. B. Leonor, F. Balas, M. Kawashita, R. L. Reis, T. Kokubo, T. Nakamura, "Biomimetic Apatite Formation on Different Polymeric Microspheres Modified with Calcium Silicate Solutions", Key Engineering Materials, Vols. 309-311, pp. 279-282, 2006
Online since
May 2006
Export
Price
$32.00
Share

In order to see related information, you need to Login.

In order to see related information, you need to Login.

Authors: S.B. Cho, Sang Bae Kim, Keon Joon Cho, Y.J. Kim, Tae Hee Lee, Y. Hwang
93
Authors: Isabel B. Leonor, Hyun Min Kim, Francisco Balas, Masakazu Kawashita, Rui L. Reis, Tadashi Kokubo, Takashi Nakamura
Abstract:Sulfonic groups (-SO3H) were covalently attached on different polymeric surfaces enabling them to induce apatite nucleation, for developing...
966
Authors: El-Sayed Ghaith, Toshihiro Kasuga, Masayuki Nogami
Abstract:Amorphous calcium silicate coating on a metallic titanium substrate for hard tissue replacement was prepared by a sol-gel method. Calcium...
235