Paper Title:
Preparation of Silica-Doped Poly(Lactic Acid) Composite Hollow Spheres Containing Calcium Carbonates
  Abstract

Silica-doped poly(lactic acid) (PLA) composite hollow spheres containing calcium carbonates (Si-CCPC spheres) were prepared using aminopropyltriethoxysilane (APTES) for injectable bone fillers combined with a cell-delivery system. Si-CCPC spheres have a hollow spherical shape of ~1 mm in the external diameter and an open channel in the shell, which is selfformed. The channel size is about 500 *m in diameter. X-ray energy dispersive spectroscopy (EDS) analysis showed incorporation of silicon in Si-CCPC spheres. After soaking Si-CCPC spheres in simulated body fluid (SBF), hydroxycarbonate apatite formed on the Si-CCPC spheres. Inductively coupled plasma atomic emission spectroscopy (ICP-AES) showed that the Si4+ ion is released from Si-CCPC spheres in SBF.

  Info
Periodical
Key Engineering Materials (Volumes 309-311)
Main Theme
Edited by
Takashi Nakamura, Kimihiro Yamashita and Masashi Neo
Pages
457-460
DOI
10.4028/www.scientific.net/KEM.309-311.457
Citation
N. Miura, H. Maeda, T. Kasuga, "Preparation of Silica-Doped Poly(Lactic Acid) Composite Hollow Spheres Containing Calcium Carbonates", Key Engineering Materials, Vols. 309-311, pp. 457-460, 2006
Online since
May 2006
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Price
$32.00
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