Paper Title:
Apatite Formation on Synthetic Polypeptide with β Sheet Structure in a Solution Mimicking Body Environment
  Abstract

Our previous study presented that sericin, a kind of silk protein, had high ability of apatite formation under a condition mimicking body environment when the sericin contains high content of β sheet structure. To confirm the effectiveness of β sheet structure on apatite nucleation, we attempted to synthesize of polypeptide containing β sheet structure and investigate apatite formation in 1.5SBF that has 1.5 times the inorganic ion concentrations of human blood plasma. Poly(FEFEFEFG) was synthesized as the polypeptide consisting mainly of β sheet structure. Formation of hydroxyapatite was observed on the film of the poly(FEFEFEFG) after soaking in 1.5SBF within 7 days. We could confirm that β sheet structure was effective even in the synthetic polypeptide.

  Info
Periodical
Key Engineering Materials (Volumes 309-311)
Main Theme
Edited by
Takashi Nakamura, Kimihiro Yamashita and Masashi Neo
Pages
489-492
DOI
10.4028/www.scientific.net/KEM.309-311.489
Citation
A. Takeuchi, C. Ohtsuki, M. Kamitakahara, S. Ogata, M. Tanihara, T. Miyazaki, "Apatite Formation on Synthetic Polypeptide with β Sheet Structure in a Solution Mimicking Body Environment", Key Engineering Materials, Vols. 309-311, pp. 489-492, 2006
Online since
May 2006
Export
Price
$32.00
Share

In order to see related information, you need to Login.

In order to see related information, you need to Login.

Authors: Xiao Liang Wang, Xu Dong Li, Xiao Min Wang, Jian Lu, Hui Chuan Zhao, Xing Dong Zhang, Zhong Wei Gu
Abstract:Collagen (Col) and chitosan (Chi) are both natural polymers and have received extensive investigation in recent years in the field of tissue...
415
Authors: Ming Xia Gou, Xu Hong Yang
Abstract:The method of extracting protein from wool was studied for the purpose of reusing the waste wool. The aqueous solution of wool keratin was...
132
Authors: Zhao Long Huang, Gui Yang Liu, Ying He, Zhong Zhou Yi, Jun Ming Guo
Abstract:To study the interaction between hydroxyapatite (HAP) and collagen in bone, we researched the phenomenon of collagen biomineralization and...
384
Authors: Zhi Ming Zhang, Shi Qian Wei, Ting Ting Li, Li Hua Han
Chapter 1: Traditional Construction Materials
Abstract:With L-glutamic acid as raw materials, N-carboxy-L-glutamic acid-benzyl-anhydride (BLG-NCA) was synthesized by triethanolamine. With...
26
Authors: Jin Hou, Jun Sheng Yuan, Ru Shang
Chapter 1: Material Science and Technology
Abstract:Polysulfone (PS) hollow fiber microporous membrane was used as substrate, the micropores of which were filled with surface-modified zeolites...
186