Paper Title:
Preparation of Poly(Lactic Acid) Hybrid Membranes Containing Silica
  Abstract

A novel poly(lactic acid) (PLA)/calcium carbonates hybrid membrane containing silica was prepared using aminopropyltriethoxysilane (APTES) for biodegradable bone guided regeneration. Carboxy groups in PLA made a chemical bond with amino groups in APTES, resulting in the formation of the hybrid membrane. The silica-hybridized PLA was an amorphous phase. The membrane formed hydroxycarbonate apatite (HCA) on its surface after 3 d of soaking in simulated body fluid (SBF). After soaking the membrane in SBF, almost no Si was present in SBF. X-ray energy dispersive spectroscopy showed the HCA layer includes Si with Ca and P. A result of osteoblast-like cellular proliferation on the membrane showed no cell-toxicity.

  Info
Periodical
Key Engineering Materials (Volumes 309-311)
Main Theme
Edited by
Takashi Nakamura, Kimihiro Yamashita and Masashi Neo
Pages
775-778
DOI
10.4028/www.scientific.net/KEM.309-311.775
Citation
H. Maeda, T. Kasuga, L. L. Hench, "Preparation of Poly(Lactic Acid) Hybrid Membranes Containing Silica", Key Engineering Materials, Vols. 309-311, pp. 775-778, 2006
Online since
May 2006
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Price
$32.00
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