Paper Title:
Bioactive Bone Cements Containing Micron-Sized Titania Particles
  Abstract

Three types of polymethylmethacrylate (PMMA)-based composite cements containing 40− 56 wt% micron-sized titania (titanium oxide) particles, designated ST2-40c, ST2-50c, and ST2-56c, were developed as bone substitutes for vertebroplasty, and evaluated for their mechanical, setting, and biological properties. In animal experiments, ST2-50c and ST2-56c were implanted into rat tibiae and solidified in situ. Their biological properties were evaluated at 6 and 12 weeks after implantation. Compressive strength, bending strength, and bending modulus increased with increasing titania content. Peak temperature during the setting reaction decreased as the filler content increased. ST2-56c had direct contact with bone over larger areas than ST2-50c at 6 and 12 weeks. Data from the present study indicated that ST2-56c is a good candidate as a bone substitute for vertebroplasty.

  Info
Periodical
Key Engineering Materials (Volumes 309-311)
Main Theme
Edited by
Takashi Nakamura, Kimihiro Yamashita and Masashi Neo
Pages
793-796
DOI
10.4028/www.scientific.net/KEM.309-311.793
Citation
K. Goto, M. Hashimoto, H. Takadama, J. Tamura, S. Fujibayashi, S. Hasegawa, K. Kawanabe, T. Kokubo, T. Nakamura, "Bioactive Bone Cements Containing Micron-Sized Titania Particles", Key Engineering Materials, Vols. 309-311, pp. 793-796, 2006
Online since
May 2006
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Price
$32.00
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