Paper Title:
Investigation on Self-Emerged Porous CPC Containing Chinese Medicine
  Abstract

In this study, biodegradable poly-lactic-acid (PLA) microspheres encapsulated with Salvia Miltiorrhiza Bunge (SMB), ranged from 100µm to 300µm, were prepared by a solvent evaporation method. Those PLA microspheres mixed with CPC powder, at a mass fraction of 0.2 to 0.8, to yield a self-emerged porous CPC. The surface morphology of PLA microspheres and CPC were observed by optical microscopy and scanning electron microscopy (SEM), respectively. The function groups of PLA microspheres and the phase composition of CPC were analyzed by Fourier transform infrared spectrometer (FTIR) and X-ray diffraction (XRD) , respectively. A preliminary study of drug release was performed by immersing PLA microspheres and CPC into simulated body fluid (SBF) for a various interval points. And the concentrations of SMB in SBF were measured by UV-VIS spectroscopy. The present results showed that the self-emerged porous CPC containing Chinese medicine could be prepared by adding biodegradable PLA microspheres. PLA microspheres can promote the CPC aqueous reaction to form final product, hydroxyapatite (HA).

  Info
Periodical
Key Engineering Materials (Volumes 309-311)
Main Theme
Edited by
Takashi Nakamura, Kimihiro Yamashita and Masashi Neo
Pages
869-872
DOI
10.4028/www.scientific.net/KEM.309-311.869
Citation
Y.R. Liu, S. X. Qu, H.F. Cheng, X. H. Li, S.B. Zhou, M.H. Li, C. Huang, R. Tan, L.L. Xiong, B. Feng, J. Weng, "Investigation on Self-Emerged Porous CPC Containing Chinese Medicine", Key Engineering Materials, Vols. 309-311, pp. 869-872, 2006
Online since
May 2006
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Price
$32.00
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