Paper Title:
MCM-41 /PCL Coated Hydroxyapatite and its Application to Drug Delivery System
  Abstract

Porous hydroxyapatite coated with MCM-41/PCL has been utilized as the matrix for controlled drug delivery. SEM result shows porous hydroxyapatite block is formed of three dimensionally inter-connected pores of 250 –300 *m in size, similar to human cancellous bone. TEM observation confirms the pore size of MCM-41 scatters about 50 Å. Ibuprofen was loaded into the pores of MCM-41 and hybridized with polycaprolactone to coat on the surface of hydroxyapatite block and controlled release profiles were studied by soaking the samples in a simulated body fluid using a UV-VIS spectrophotometer.

  Info
Periodical
Key Engineering Materials (Volumes 309-311)
Main Theme
Edited by
Takashi Nakamura, Kimihiro Yamashita and Masashi Neo
Pages
911-914
DOI
10.4028/www.scientific.net/KEM.309-311.911
Citation
Y. Kim, K. J. Kim, S. R. Kim, H. W. Lee, "MCM-41 /PCL Coated Hydroxyapatite and its Application to Drug Delivery System ", Key Engineering Materials, Vols. 309-311, pp. 911-914, 2006
Online since
May 2006
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Price
$32.00
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