Cylindrical shell is a kind of common used structure in engineering. Interest in the response of cylindrical shells to local impact loading has increased over the last few years. A structure always endures working load more or less. For a cylindrical shell, the working load commonly is internally pressure. In this paper, a numeral simulation of wedge block impact internally Pressured cylindrical shell was carried out. The dynamic failure process of the structure was obtained. The consistency between experimental observation and numerical simulation is satisfactory.