Paper Title:
Comparison of Osteoinduction by Autologous Bone and Biphasic Calcium Phosphate Ceramic in Goats
  Abstract

Autologous bone chips are widely used in orthopedic surgery to fill large defects due to osteoinductive property but are limited in quantity. Several groups have reported the formation of mineralized bone after implantation of bioceramics in ectopic sites of different animals. However, osteoinduction by bioceramics has not yet proved to be equivalent to those of autologous bone. In this study, we compare the bone inducing capability of autologous bone chips and synthetic biphasic calcium phosphate (BCP) ceramics granules sintered at various temperatures. Both materials were implanted in muscles and femurs of goats inside hollow containers for 6, 12 and 24 weeks and analyzed by histology. This study showed that bone tissue formed in contact with micro porous ceramics sintered at low temperature as well as autologous bone chips both in ectopic and intrafemoral sites of goats.

  Info
Periodical
Key Engineering Materials (Volumes 330-332)
Main Theme
Edited by
Xingdong Zhang, Xudong Li, Hongsong Fan, Xuanyong Liu
Pages
1063-1066
DOI
10.4028/www.scientific.net/KEM.330-332.1063
Citation
B. H. Fellah, O. Gauthier, P. Weiss, D. Chappard, P. Layrolle, "Comparison of Osteoinduction by Autologous Bone and Biphasic Calcium Phosphate Ceramic in Goats", Key Engineering Materials, Vols. 330-332, pp. 1063-1066, 2007
Online since
February 2007
Export
Price
$32.00
Share

In order to see related information, you need to Login.

In order to see related information, you need to Login.

Authors: Oliver Malard, Jean Michel Bouler, Jerome Guicheux, Olivier Gauthier, E. Lerouxel, G. Daculsi
Abstract:Bone invasion is common in case of Squamous Cell Carcinomas (SCC) of the upper aero-digestive tract. Radiotherapy is required in addition to...
285
Authors: Min Sung Park, Young Mee Jung, Soo Hyun Kim, Sang Heon Kim, Young Ha Kim, Byoung Goo Min, Jin Woo Lee
Abstract:Poly-L-lactic acid (PLLA) is a desirable and very attractive polymer for fabricating porous scaffolds. As of now, a solvent casting method...
145
Authors: Borhane H. Fellah, Said Kimakhe, G. Daculsi, Pierre Layrolle
Abstract:This study aims at evaluating bone growth in critical-sized femoral defects of rats filled with macro micro porous biphasic calcium...
439
Authors: Franck Jegoux, Eric Aguado, Ronan Cognet, Oliver Malard, Françoise Moreau, G. Daculsi, Eric Goyenvalle
Abstract:The aim of this study was to study bone marrow quality from various location and species for reconstruction of segmental critical size...
1245
Authors: Sandris Petronis, Janis Locs, Vita Zalite, Mara Pilmane, Andrejs Skagers, Ilze Salma, Girts Salms
Chapter 4: Biomaterials and Applications in Biomedical Engineering
Abstract:Calcium bone substitutes are successfully used for local recovery of osteoporotic bone and filling of bone defects. Previous studies revieled...
229