Gene Expression Profile of Osteoblast-Like Cells on Calcium Phosphate Biomaterials |
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| Journal | Key Engineering Materials (Volumes 330 - 332) |
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| Volume | Bioceramics 19 |
| Edited by | Xingdong Zhang, Xudong Li, Hongsong Fan, Xuanyong Liu |
| Pages | 1087-1090 |
| DOI | 10.4028/www.scientific.net/KEM.330-332.1087 |
| Citation | Taro Takemura et al., 2007, Key Engineering Materials, 330-332, 1087 |
| Online since | February, 2007 |
| Authors | Taro Takemura, Hong Song Fan, Toshiyuki Ikoma, Junzo Tanaka, Nobutaka Hanagata |
| Keywords | Biphasic Calcium Phosphate (BCP), DNA Microarray, Gene Expression, Hydroxyapatite (HA), Osteoblast, Tricalcium Phosphate |
| Abstract | Gene expression profile of osteoblast-like cells cultured on dense disk materials and porous materials of calcium phosphate ceramics was constructed from DNA microarray analyses. The profile revealed that gene expression patterns of porous materials were significantly different from those of dense disk materials. The porous materials had a capacity to induce expressions of genes involved in osteoblast differentiation, while dense disk materials regulated gene expressions related to osteoclastogenesis. |
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