Paper Title:
Preparation of Porous Organically-Modified Silicate Hybrids for Cell Culture Matrix
  Abstract

Porous & rubbery organic-inorganic hybrids were synthesized from tetraethoxysilane (TEOS) and polydimethylsiloxane (PDMS) through a sol-gel route using sieved sucrose granules as a porogen. The porous hybrids with a high content of PDMS behaved like polymer sponge. The porosity was over 90% irrespective of the hybrid composition and the pore diameter ranged from 100 to 500 μm. In the three-dimensional cell culture, mammalian cells were well cultured in the porous hybrids. The present results indicate that the hybrids may be a promising scaffold for developing such functional culture methods.

  Info
Periodical
Key Engineering Materials (Volumes 330-332)
Main Theme
Edited by
Xingdong Zhang, Xudong Li, Hongsong Fan, Xuanyong Liu
Pages
1177-1180
DOI
10.4028/www.scientific.net/KEM.330-332.1177
Citation
K. Tsuru, S. Hayakawa, Y. Shirosaki, T. Okayama, K. Kataoka, N.H. Huh, A. Osaka, "Preparation of Porous Organically-Modified Silicate Hybrids for Cell Culture Matrix", Key Engineering Materials, Vols. 330-332, pp. 1177-1180, 2007
Online since
February 2007
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Price
$32.00
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