Paper Title:
Bone Formation Effect of HA/β-TCP Composite Powders in Rabbit Calvarial Bone Defects: Histologic Study
  Abstract

This study evaluated the histology results of surgically created bone cavities in the calvaria of rabbits that were subsequently filled with a HA/ß-TCP composite powder developed in Korea (Dentium, Korea). Ten young adult rabbits were used. Four defects were surgically produced in the calvaria of each rabbit. These defects were classified into 4 groups: the control group, no graft materials; experimental group I, normal saline + graft materials; experimental group II, venous blood + graft materials; and experimental group III, graft materials only. The defects were randomly filled with the graft materials. The rabbits were sacrificed with at 1-, 2-, 4-, 6- and 8- weeks after surgery. The histology specimens were prepared using the general method with H & E staining at a 6 ㎛ thickness. Histologically, the degree of new bone formation was similar in all experimental groups. However, for experimental group II, many cells had gathered around the graft materials 1-week after surgery, and new bone formed slightly faster and than in the other groups. No bone formation was observed in the control group. Based on histology findings, the new HA/ß- TCP composite powders appeared to act as a scaffolding material for the regeneration of osseous defects.

  Info
Periodical
Key Engineering Materials (Volumes 330-332)
Main Theme
Edited by
Xingdong Zhang, Xudong Li, Hongsong Fan, Xuanyong Liu
Pages
1331-1334
DOI
10.4028/www.scientific.net/KEM.330-332.1331
Citation
H. S. Jang, K. H. Lee, M. J. Jeong, J. C. Park, H. J. Kim, Y. S. Kwon, C. K. Kim, B. O. Kim, "Bone Formation Effect of HA/β-TCP Composite Powders in Rabbit Calvarial Bone Defects: Histologic Study", Key Engineering Materials, Vols. 330-332, pp. 1331-1334, 2007
Online since
February 2007
Export
Price
$32.00
Share

In order to see related information, you need to Login.

In order to see related information, you need to Login.

Authors: J.S. Kim, S.Y. Na, Y.H. Kown, J.B. Park, J.H. Chung, M.I. Cho, Y. Herr
Abstract:The purpose of this study was to examine if the application of titanium-reinforced expanded polytetrafluoroethylene(TR-ePTFE) membrane...
1075
Authors: Sung Koo Kim, Jung Seok Lee, Gyung Joon Chae, Ui Won Jung, Yong Keun Lee, Chong Kwan Kim, Seong Ho Choi
Abstract:This study evaluated periodontal repair and biomaterial reaction following implantation of a newly fabricated calcium phosphate chitosan...
393
Authors: C.S. Lim, S.G. Kim, Sung Chul Lim
Abstract:We evaluated the bone healing effect of grafting with synthetic β-tricalcium phosphate (β-TCP; Cerasorb®), bovine-derived hydroxyapatite...
1261
Authors: H. Valiense, G.V.O. Fernandes, B. Moura, J. Calasans-Maia, A. Alves, Antonella M. Rossi, J.M. Granjeiro, M. Calasans-Maia
Abstract:The objective of this study was to investigate the bone repair of carbonate apatite (cHA) in comparison to hydroxyapatite (HA, control...
258
Authors: Lan Lei Wang, Ji Hua Li, Yong Tao Xie, Pi Shan Yang, Yun Mao Liao, Gong Ling Guo
Chapter 2: Materials Science and Engineering
Abstract:The aim of the present study is to investigate the efficacy of nanobiphasic calcium phosphate (nanoBCP) bioceramic in the treatment of...
422